A type of immunotherapy used to find and destroy specific cells within the body (for example, the cells where follicular lymphoma starts). Antibody treatment can also harm healthy cells in the body.
Bispecific antibodies are designed to target 2 different sites on different cells or the same cell. For example, a bispecific antibody binding to 2 different cells is thought to bring the cells together, such as an immune cell and cancer cell.
The soft spongy material that fills the inside of bones. Bone marrow is the source of new blood cells, and platelets are made in the bone marrow.
Also called complete response—the disappearance of all signs of cancer in response to treatment. This does not mean the cancer has been cured.
A side effect when your immune system responds too strongly by rapidly releasing a large amount of substances known as cytokines. It may cause fever, nausea, or other symptoms.
The most common type of indolent non-Hodgkin’s lymphoma (NHL). With NHL, abnormal lymphocytes build up in the lymph nodes, bone marrow, and spleen. FL can be a chronic disease.
Small bean-shaped organs that store white blood cells.
A partial or complete remission.
Also called partial response—some measurable decrease in size of the cancer.
The second phase of a clinical trial that studies an investigational treatment to test how well it works and monitors for potential side effects.
A term used to describe disease that has not responded to previous treatment.
A term used to describe disease that has returned after responding to previous treatment.
A term used to describe a response to treatment. Partial remission means the cancer is significantly improved, but evidence of the cancer remains. Complete remission means all evidence of the cancer is gone for a period of time. Overall response is a term that may be used when speaking about remission and means any partial or complete remission.
An organ that is part of the lymphatic system. The spleen makes lymphocytes, filters blood, stores blood cells, and destroys old blood cells. It is located on the left side of the abdomen near the stomach.
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